And that’s the whole point of treating aging as the ultimate disease, the one that effectively produces all the others. (For example, Sinclair writes, smoking makes lung cancer five times more likely, but just living from 20 to 70 increases your chances of getting the disease a thousandfold, even if you’ve never sucked on a cancer stick. “Aging is by far the biggest risk factor in any disease, by an order of magnitude,” Sinclair says; having volunteered in nursing homes with his wife, he knows whereof he speaks. “Don’t delude yourself: Getting old and getting sick is not fun, for you or for your family.
We’ve known for some years that resveratrol reduces blood pressure; turns out it also boosts NAD. (For a long time we thought resveratrol was beneficial because it was an antioxidant, but biologists like Sinclair have started to shy away from the oxidizing theory of aging. ) And then there’s Metformin, one of the most widely-used diabetes drugs, which has also been shown to have anti-aging properties.
I’m not brave enough to try Prolon, a five-day, $250 precision starvation diet originally developed for chemo patients that is all the rage in longevity-obsessed Silicon Valley this year. (Sample day: olives, herbal tea, a tiny nut bar, a packet of kale crackers. ) But it just so happened that when I talked to Sinclair, my wife had insisted that we rein in our eating habits with one of our periodic Whole30 diets (a month where you only eat protein, vegetables, fruit, nuts and seeds, but can have as much as you like).
There are other brand new drugs in the works, many of which Sinclair can’t talk about, that he says “will make what we have today look like doctors using leeches. ” But he does predict that within the next few decades, doctors will start injecting us with a benign designer virus that can literally reprogram our genome to be young again.
That can cause tumors, collapsed capillaries, and other horrific cellular mistakes. “This loss of information is what leads each of us into a world of heart disease, cancer, pain, frailty and death,” says Sinclair.
The end of aging: Are you ready to live to 150? https://t.co/A0pfmo3F3z— Mashable (@mashable) September 7, 2020
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